VAMP-1, VAMP-2, and syntaxin-4 regulate ANP release from cardiac myocytes
نویسندگان
چکیده
منابع مشابه
Association of VAMP-2 and Syntaxin 1A Genes with Adult Attention Deficit Hyperactivity Disorder
OBJECTIVE The etiology of attention deficit hyperactivity disorder (ADHD) has not been entirely clarified yet. Structural and metabolic differences at the prefrontal striatal cerebellary system and the interaction of gene and environment are the main factors that thought to play roles in the etiology. Genetic investigations are performed especially about the dopamine pathways and receptors. In ...
متن کاملEctopic expression of syntaxin 1 in the ER redirects TI-VAMP- and cellubrevin-containing vesicles.
SNARE proteins are key mediators of membrane fusion. Their function in ensuring compartmental specificity of membrane fusion has been suggested by in vitro studies but not demonstrated in vivo. We show here that ectopic expression of the plasma membrane t-SNARE heavy chain syntaxin 1 in the endoplasmic reticulum induces the redistribution of its cognate vesicular SNAREs, TI-VAMP and cellubrevin...
متن کاملSyntaxin, VAMP, and Rab3 are selectively expressed during sea urchin embryogenesis.
SNARE and rab protein family members were originally identified in terminally differentiated cell types. These proteins are phylogenetically conserved and while compelling evidence demonstrates their involvement in the secretory pathway, their exact function is debated. We recently identified SNARE protein family members in the sea urchin egg and provided evidence that rab3 functions in the exo...
متن کاملThe exocytosis regulatory proteins syntaxin and VAMP are shed from sea urchin sperm during the acrosome reaction.
Syntaxin is a cytoplasmically oriented plasma membrane protein and VAMP (vesicle-associated membrane protein; synaptobrevin) is a protein associated with the secretory vesicle membrane. These two proteins form part of a complex which is thought to mediate the fusion of plasma and vesicle membranes during exocytosis. This paper reports the identification of syntaxin and VAMP homologues in sea ur...
متن کاملVAMP/synaptobrevin isoforms 1 and 2 are widely and differentially expressed in nonneuronal tissues
VAMP/synaptobrevin is part of the synaptic vesicle docking and fusion complex and plays a central role in neuroexocytosis. Two VAMP (vesicle-associated membrane protein) isoforms are expressed in the nervous system and are differently distributed among the specialized parts of the tissue. Here, VAMP-1 and -2 are shown to be present in all rat tissues tested, including kidney, adrenal gland, liv...
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ژورنال
عنوان ژورنال: Journal of Molecular and Cellular Cardiology
سال: 2010
ISSN: 0022-2828
DOI: 10.1016/j.yjmcc.2010.08.020